The Immunology Database and Analysis Portal (ImmPort) has been developed for the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Allergy, Division of Allergy, Immunology, and Transplantation (DAIT). Data on ImmPort focuses on all areas of immunological research. ImmPort collects data both from clinical and mechanistic studies on human subjects and from immunology studies on model organisms.
Data on ImmPort
Currently, de-identified omics datasets from more than 300 studies are shared through the repository with a primary focus on allergy, autoimmune diseases, infection responses, transplantation, and vaccine responses. Data types housed in ImmPort include subject assessments i.e., medical history, concomitant medications, and adverse events as well as mechanistic assay data such as flow cytometry, ELISA, ELISPOT, Proteomic Array, Hemagglutination inhibition (HAI) assay, DNA Methylation panel, and TCR Diversity Matrix, Cytokine/Chemokine panel and Next-generation Sequencing.
Gene Sets on ImmPort
The gene list on ImmPort can be found here: https://www.immport.org/shared/genelists
Using Data on ImmPort
How to Look for Data on ImmPort?
On the ‘Shared Data’ page on immport.org, an unfiltered list of available studies is found. You can filter for studies based on study types, research focus, species, and biosample types. Filtering through studies using keywords is also available.
How to Download Data from ImmPort?
Once you have browsed and selected the study of interest, you can download the study in 3 ways. First, click on ‘Download All Data’ on the Shared Data homepage to download the information of all datasets present in the list on that page. Alternatively, press the ‘Download’ button next to the individual study that you want to save.
Authors citing data sets that they uploaded to ImmPort to support a publication, include the following example text in your Acknowledgements: ‘The data supporting this publication is available at ImmPort (https://www.immport.org) under study accession SDY1234′
When referencing ImmPort as a resource for publication: ImmPort, toward repurposing of open access immunological assay data for translational and clinical research. Bhattacharya S, Dunn P, Thomas CG, Smith B, Schaefer H, Chen J, Hu Z, Zalocusky KA, Shankar RD, Shen-Orr SS, Thomson E, Wiser J, Butte AJ. Sci Data. 2018 Feb 27;5:180015. doi: 10.1038/sdata.2018.15.