Products

Our products are built to take researchers from raw data to biological insights quickly and efficiently. We design for reproducibility, ease-of-use, and speed. We collaborate with leading academic and industrial labs in the fields of metabolomics, genomics, transcriptomics, and integrated omics to bring the latest techniques to our partners.

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PollyTM

PollyTM is a one-stop data analysis platform designed to accelerate the drug discovery process. PollyTM can host multiple applications that can be combined by users to create their own analytical workflows. A few clicks are all that are required to perform end-to-end computations and achieve a deeper understanding of the experimental data.

PollyTM currently hosts applications for 13C metabolic labeling data analysis and visualization for LC-MS and LC-MS/MS workflows. As PollyTM grows, we envision adding applications for other computation-heavy areas of drug discovery and enable integrated omics analyses. The platform will soon allow users to host their own applications as well.

Drug Hunter

Drug Hunter is an interactive web-based application that enables scientists to create a virtual project plan to deliver a clinical candidate. Using a drug discovery simulation exercise, teams adjust their lead optimization plans as they get real-time warnings. Each team has the freedom to structure their testing paradigm by defining a key hypothesis and critical questions. At the end of the simulation, Drug Hunter provides an evaluation of each plan using metrics like cost, time, and probability of success. The tool teaches scientists how their decisions influence the efficiency and success of their projects. Drug Hunter helps illustrate that lean thinking is as critical to a team’s success as the underlying science

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El-MAVEN

El-MAVEN is an LC-MS data processing engine for large-scale metabolomic experiments. It allows automated processing of raw LC-MS data from unlabeled and labeled, targeted and untargeted metabolomic profiling experiments. It is vendor-neutral, open-source and has an interface built for ease of processing and visualizing hundreds of samples.

The project was originally developed as MAVEN at the Rabinowitz Lab at Princeton University. Over the last year, Elucidata has revamped the software architecture of the tool to make it capable of handling large datasets - tens of GBs (thousands of samples). In the process, we have also made it faster and more robust.

We continue to actively develop the application with support from our collaborators. Elucidata offers support for deployment, maintenance and training users. We also develop customized features for El-MAVEN for our partners to accommodate special requirements.

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PollyTM QuantFit

PollyTM QuantFit is used for quantifying metabolomic data using standard samples with known concentrations. It allows the user to fit a range of functions like linear, polynomial or exponential with different parameters. The tool shows intuitive visualizations at all stages to aid the user in the iterative process of getting to the best fits.

PollyTM QuantFit allows many different kinds of fits - linear, polynomial, exponential and log-log. The user can reject data or assign different weights to different data points. Detailed log maintains a useful of what the user has done. At the end, the user can download the outputs to be visualized in a tool of their choice.

PollyTM IsoCorrect

PollyTM IsoCorrect performs natural abundance correction for LC-MS data from a labeling experiment. The web interface allows working with metabolite intensities taken from softwares such as Multiquant, MAVEN, TraceFinder, QI etc.

PollyTM IsoCorrect is capable of processing both LC-MS/MS and LC-MS data. It has specialized algorithms for both high resolution and low resolution data. All outputs are combined with metadata in a downloadable format which can go into visualisation tools directly. It can process large datasets, thus reducing time taken to perform natural abundance correction from weeks to minutes. An automated workflow also eliminates chances of mistakes from manual calculations.

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